BDBM221048 US9284322, varenicline::US9303017, Varenicline
SMILES C1[C@H]2CNC[C@@H]1c1cc3nccnc3cc21
InChI Key InChIKey=JQSHBVHOMNKWFT-DTORHVGOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 221048
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute
US Patent
Research Triangle Institute
US Patent
Affinity DataKi: 32.5nMpH: 7.4Assay Description:Adult male rat cerebral cortices (Pel-Freez Biologicals, Rogers, Ark.) were homogenized (polytron) in 39 volumes of ice-cold 50 mM Tris buffer (assay...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute
US Patent
Research Triangle Institute
US Patent
Affinity DataKi: 37nM ΔG°: -9.42kcal/molepH: 7.4 T: 2°CAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm^2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris....More data for this Ligand-Target Pair